M. Florine Démosthène was born in the United States and raised between Port-au-Prince, Haiti and New York. Démosthène earned her Bachelor of Fine Arts from Parsons School for Design in New York and her Master of Fine Arts from Hunter College-City University of New York.
She has exhibited extensively through group and solo exhibitions in the USA, Caribbean, UK, Europe and Africa, with recent solo exhibitions including, Between Possibility and Actuality at Mariane Ibrahim Gallery Chicago, a solo booth exhibition with Mariane Ibrahim Gallery at the The New York Armory Fair and The Stories I Tell Myself at Gallery 1957, Ghana). She is the recipient of a Tulsa Artist Fellowship, Arts Moves Africa Grant and a Joan Mitchell Foundation Grant.
She has participated in residencies in the USA, UK, Slovakia, Ghana and Tanzania. Her work can be seen at the University of South Africa (UNISA), Lowe Museum of Art, PFF Collection of African American Art and in various private collections worldwide.